Description

2-(4-m-Tolyl-Tetrahydro-2H-Pyran-4-Yl)Acetic Acid is a high-purity, synthetically derived organic acid featuring a unique molecular scaffold combining a tetrahydro-2H-pyran ring with a tolyl substituent. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in sophisticated organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Organic Synthesis Building Block: Used in medicinal chemistry and material science for constructing complex molecular architectures due to its functionalized acetic acid group and rigid pyran core.
• Ligand and Catalyst Development: Employed in the research and development of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Integral to the manufacture of high-value specialty chemicals, including dyes, pigments, and performance additives.
• Academic and R&D: Used in university and corporate research laboratories for method development, structure-activity relationship (SAR) studies, and exploring new chemical entities.

Basic Information

Product Name	2-(4-m-Tolyl-Tetrahydro-2H-Pyran-4-Yl)Acetic Acid
CAS No.	1225797-27-2
Molecular Formula	C14H18O3
Molecular Weight	234.29 g/mol
Synonyms	2-[4-(3-Methylphenyl)oxan-4-yl]acetic acid; 2-(4-(m-Tolyl)tetrahydro-2H-pyran-4-yl)acetic acid; 4-(3-Methylphenyl)tetrahydro-2H-pyran-4-acetic acid; 2-(4-(3-Methylphenyl)tetrahydro-2H-pyran-4-yl)ethanoic acid; 1225797-27-2; m-Tolyl-THP-acetic acid derivative; 4-(m-Tolyl)-4-(carboxymethyl)tetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our production of 2-(4-m-Tolyl-Tetrahydro-2H-Pyran-4-Yl)Acetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and compliance with REACH regulations ensures a reliable supply of material suitable for demanding global industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to minimize exposure to atmospheric humidity. Store away from strong oxidizing agents, strong bases, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.