Description

2-[4-(3-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is a high-purity, functionalized organic acid building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a chlorophenyl-substituted tetrahydropyran ring, makes it a valuable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research and development teams, as well as process chemists, in the pharmaceutical, agrochemical, and specialty fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed as a monomer or functional additive in the synthesis of advanced polymers with specific thermal or optical properties.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	2-[4-(3-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid
CAS No.	1225768-54-6
Molecular Formula	C₁₃H₁₅ClO₃
Molecular Weight	254.71 g/mol
Synonyms	2-[4-(3-Chlorophenyl)oxan-4-yl]acetic acid; 4-(3-Chlorophenyl)-4-(carboxymethyl)tetrahydro-2H-pyran; (4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-yl)acetic acid; 2-(4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-yl)acetic acid; 1225768-54-6; 3-Chlorophenyl tetrahydropyran acetic acid derivative
EINECS	Contact for details

Quality Control

Our 2-[4-(3-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate engineering controls and personal protective equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.