Description

2-[4-(4-Methoxyphenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is essential for research and development chemists, process development scientists, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or other specialized therapeutic areas.
• Organic Synthesis Building Block: Utilized in research laboratories for constructing complex molecules due to its tetrahydro-2H-pyran (oxane) and acetic acid functional groups.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities with potential biological activity.
• Process Chemistry & Scale-Up: Used in the development and optimization of scalable synthetic routes for the production of target molecules under current Good Manufacturing Practice (cGMP) standards.
• Fine Chemical Production: Employed in the manufacture of specialized, high-value chemicals for agrochemical or material science applications requiring specific chiral or structural motifs.

Basic Information

Product Name	2-[4-(4-Methoxyphenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid
CAS No.	1225481-64-0
Molecular Formula	C14H18O4
Molecular Weight	250.29 g/mol
Synonyms	2-[4-(4-Methoxyphenyl)oxan-4-yl]acetic acid; 4-(4-Methoxyphenyl)-4-(carboxymethyl)tetrahydro-2H-pyran; 2-(4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)acetic acid; (4-(4-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)acetic acid; 2-[4-(4-Methoxyphenyl)tetrahydropyran-4-yl]acetic acid; 4-(4-Methoxyphenyl)-4-(2-carboxyethyl)tetrahydro-2H-pyran (tautomeric form).
EINECS	Contact for details

Quality Control

Our 2-[4-(4-Methoxyphenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.