Description

(Sp)-1-[(R)-tert-Butylphosphinoyl]-2-[(R)-1-(Diphenylphosphino)Ethyl]Ferrocene is a highly specialized, chiral ferrocenyl phosphine ligand designed for asymmetric catalysis. This compound is valued for its ability to induce high enantioselectivity in critical transition metal-catalyzed reactions, providing a significant advantage in the synthesis of optically pure intermediates. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• As a privileged ligand for asymmetric hydrogenation of prochiral olefins, ketones, and imines.
• Key chiral inducer in rhodium- and ruthenium-catalyzed C-C and C-X bond-forming reactions.
• Critical component in the synthesis of enantiomerically pure pharmaceutical intermediates, such as β-amino acids and chiral alcohols.
• Use in academic and industrial R&D for methodology development in asymmetric synthesis.
• Catalyst for the production of specialty agrochemicals and flavors & fragrances requiring high optical purity.
• Potential application in material science for creating chiral polymers or surfaces.

Basic Information

Product Name	(Sp)-1-[(R)-tert-Butylphosphinoyl]-2-[(R)-1-(Diphenylphosphino)Ethyl]Ferrocene
CAS No.	1221745-90-9
Molecular Formula	C28H32FeOP2
Molecular Weight	510.34 g/mol
Synonyms	(R,R)-Tert-Butylferrocenylphosphine-phosphinite ligand; (R,R)-t-Bu-FerroPhos; JosiPhos SL-J009-1 type ligand; (R)-(+)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl di-tert-butylphosphine oxide; (R,R)-1-[(tert-Butylphosphinyl)]-2-[(1-(diphenylphosphino)ethyl)]ferrocene; Ferrocenyl Josiphos-type ligand; Chiral ferrocenyl phosphine-phosphinite.
EINECS	Contact for details

Quality Control

Our production of (Sp)-1-[(R)-tert-Butylphosphinoyl]-2-[(R)-1-(Diphenylphosphino)Ethyl]Ferrocene adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and residual solvent content is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.