Description

5-Fluoro-4-Azachroman-3-One is a high-purity fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring a fused azachromanone core with a fluorine substituent, makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for creating advanced organic materials, such as liquid crystals, organic semiconductors, or specialty polymers.
• Chemical Biology Probe: Employed in academic and industrial research to develop molecular probes for studying enzyme mechanisms or biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	5-Fluoro-4-Azachroman-3-One
CAS No.	1221502-66-4
Molecular Formula	C11H8FNO2
Molecular Weight	205.19 g/mol
Synonyms	5-Fluoro-4-azachroman-3-one; 4-Azachroman-3-one, 5-fluoro-; 5-Fluoro-1,4-benzoxazin-3(4H)-one; 5-Fluoro-3,4-dihydro-1,4-benzoxazin-3-one; 5-Fluoro-4H-1,4-benzoxazin-3-one; 1221502-66-4
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-Azachroman-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.