Description

n-(Piperidin-4-Yl)-Tetrahydro-2H-Pyran-4-Carboxamide Hydrochloride is a high-purity chemical intermediate with the CAS registry number 1220031-94-6. This compound is valued for its role as a critical building block in the synthesis of complex pharmaceutical molecules, particularly in medicinal chemistry research and development. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery of new therapeutic agents, especially within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR).
• CNS Drug Development: Serves as a building block for potential therapeutics targeting neurological disorders, leveraging the piperidine moiety.
• Oncology Research: Employed in the synthesis of candidate molecules designed to inhibit specific biological pathways involved in cancer.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Process Chemistry & Scale-up: Supports route scouting and optimization for the commercial-scale manufacturing of developmental drugs.

Basic Information

Product Name	n-(Piperidin-4-Yl)-Tetrahydro-2H-Pyran-4-Carboxamide Hydrochloride
CAS No.	1220031-94-6
Molecular Formula	C11H21ClN2O2
Molecular Weight	248.75 g/mol
Synonyms	4-[(Oxane-4-carbonyl)amino]piperidine hydrochloride; Tetrahydro-2H-pyran-4-carboxamide, N-4-piperidinyl-, hydrochloride; 1-(Tetrahydro-2H-pyran-4-ylcarbonyl)-4-piperidinamine hydrochloride; 4-Piperidinamine, N-(tetrahydro-2H-pyran-4-ylcarbonyl)-, hydrochloride; Piperidine-4-carboxylic acid tetrahydro-pyran-4-ylamide hydrochloride
EINECS	Contact for details

Quality Control

Our n-(Piperidin-4-Yl)-Tetrahydro-2H-Pyran-4-Carboxamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.