Description

2-(1-Ethylpyrrolidin-3-Yl)Acetic Acid CAS NO 1220027-60-0 is a high-purity pyrrolidine derivative, a versatile chiral building block and intermediate of significant value in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a tertiary amine within a constrained ring system, makes it a critical precursor for constructing complex molecules with specific stereochemistry and biological activity. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of central nervous system (CNS) drugs, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where its structural motif can contribute to biological efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Chemical Research & Development: Employed as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Specialty Polymer Modification: Can be utilized to introduce functional amine and acid groups into polymer chains, modifying properties for specific industrial applications.

Basic Information

Product Name	2-(1-Ethylpyrrolidin-3-Yl)Acetic Acid
CAS No.	1220027-60-0
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	2-(1-Ethyl-3-pyrrolidinyl)acetic acid; 1-Ethyl-3-pyrrolidineacetic acid; 3-Carboxymethyl-1-ethylpyrrolidine; (1-Ethylpyrrolidin-3-yl)acetic acid; NSC 405124; 2-(1-Ethylpyrrolidin-3-yl)ethanoic acid; 2-(N-Ethyl-3-pyrrolidinyl)acetic acid
EINECS	Contact for details

Quality Control

Our 2-(1-Ethylpyrrolidin-3-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.