Description

3-Azetidinyl Tetrahydro-2H-Pyran-4-Carboxylate CAS NO 1220021-11-3 is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine-pyrone hybrid scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in early-stage drug discovery.
• Protease Inhibitor Development: The structural motif is relevant for the design and synthesis of potential protease inhibitors.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Serves as a starting material for contract manufacturing organizations (CMOs) producing specialized APIs for clinical trials.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	3-Azetidinyl Tetrahydro-2H-Pyran-4-Carboxylate
CAS No.	1220021-11-3
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	3-Azetidinyloxan-4-carboxylate; Tetrahydro-2H-pyran-4-carboxylic acid azetidin-3-yl ester; 3-(Oxan-4-yloxycarbonyl)azetidine; Azetidin-3-yl tetrahydro-2H-pyran-4-carboxylate; 4-Carboxyoxane-3-azetidinyl ester; 1220021-11-3; 3-Azetidinyl THP-4-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Azetidinyl Tetrahydro-2H-Pyran-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.