Description

4-Piperidinylmethyl Tetrahydro-2H-Pyran-4-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on drug discovery programs targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic candidates.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Neurological Disorder Research: Applied in the R&D of compounds targeting central nervous system (CNS) pathways.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying biological mechanisms and target validation.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot and commercial production scales.

Basic Information

Product Name	4-Piperidinylmethyl Tetrahydro-2H-Pyran-4-Carboxylate Hydrochloride
CAS No.	1219980-05-8
Molecular Formula	C13H23NO3·HCl
Molecular Weight	277.79 g/mol (Free base: 241.33 g/mol)
Synonyms	4-((Piperidin-4-yl)methyl)tetrahydro-2H-pyran-4-carboxylic acid hydrochloride; Tetrahydro-2H-pyran-4-carboxylic acid, 4-[(4-piperidinyl)methyl]-, hydrochloride; 4-(Piperidin-4-ylmethyl)oxane-4-carboxylic acid hydrochloride; 4-Piperidin-4-ylmethyl-tetrahydropyran-4-carboxylic acid hydrochloride; 4-Piperidinylmethyl THP-4-carboxylate HCl; (4-Piperidinylmethyl)tetrahydropyran-4-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Piperidinylmethyl Tetrahydro-2H-Pyran-4-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.