Description

2-(4-Piperidinyl)Ethyl Tetrahydro-2H-Pyran-4-Carboxylate Hydrochloride is a high-purity, non-racemic pharmaceutical intermediate and building block of significant interest in modern organic synthesis. Its core value lies in its piperidine and tetrahydropyran motifs, which are privileged scaffolds for constructing bioactive molecules with enhanced pharmacokinetic properties. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on central nervous system (CNS) agents, receptor modulators, and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in neurological and psychiatric drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic candidates.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein function.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient manufacturing of complex drug molecules.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis providers offering bespoke chemical services to the life sciences industry.

Basic Information

Product Name	2-(4-Piperidinyl)Ethyl Tetrahydro-2H-Pyran-4-Carboxylate Hydrochloride
CAS No.	1219956-80-5
Molecular Formula	C13H24ClNO3
Molecular Weight	277.79 g/mol
Synonyms	2-(Piperidin-4-yl)ethyl tetrahydro-2H-pyran-4-carboxylate hydrochloride; Tetrahydro-2H-pyran-4-carboxylic acid 2-(4-piperidinyl)ethyl ester hydrochloride; 4-Piperidineethanol, β-(tetrahydro-2H-pyran-4-ylcarbonyl)-, hydrochloride; (2-(Piperidin-4-yl)ethyl) tetrahydro-2H-pyran-4-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Piperidinyl)Ethyl Tetrahydro-2H-Pyran-4-Carboxylate Hydrochloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing results from HPLC, NMR, and other relevant tests is provided with each shipment to guarantee supply reliability and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.