Description

2-(2-Hydroxy-4,5-Dihydro-3H-1-Benzazepin-3-Yl)-6-Phenylpyridazin-3(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly targeting central nervous system (CNS) disorders. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzazepine and pyridazine-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for potential CNS-active compounds.
• Preclinical Development: Serves as a critical material for producing batches of active pharmaceutical ingredients (APIs) for toxicology and early-phase clinical studies.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(2-Hydroxy-4,5-Dihydro-3H-1-Benzazepin-3-Yl)-6-Phenylpyridazin-3(2H)-One
CAS No.	1219577-08-8
Molecular Formula	C22H19N3O2
Molecular Weight	357.41 g/mol
Synonyms	6-Phenyl-2-(2-hydroxy-4,5-dihydro-3H-1-benzazepin-3-yl)pyridazin-3(2H)-one; 2-(2-Hydroxy-4,5-dihydro-3H-1-benzazepin-3-yl)-6-phenyl-2,3-dihydropyridazin-3-one; 1219577-08-8; Benzazepine-pyridazinone derivative; 3-(6-Oxo-3-phenyl-6H-pyridazin-1-yl)-4,5-dihydro-1H-2-benzazepin-2-ol
EINECS	Contact for details

Quality Control

Our 2-(2-Hydroxy-4,5-Dihydro-3H-1-Benzazepin-3-Yl)-6-Phenylpyridazin-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The material may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.