Description

2-(4-Bromo-2-Fluorobenzyl)-6-(4-Methoxyphenyl)Pyridazin-3(2H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to develop next-generation drug candidates, leveraging its specific bromo-fluoro and methoxyphenyl substituents for precise biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used by R&D scientists for structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable pyridazinone core.
• API Development: Integral in the development and scale-up processes for new active pharmaceutical ingredients, requiring high chemical purity and batch-to-batch consistency.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a pharmacological probe to study specific enzyme or receptor interactions.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for client projects.
• Academic Research: Used in university and institutional laboratories for cutting-edge research in organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	2-(4-Bromo-2-Fluorobenzyl)-6-(4-Methoxyphenyl)Pyridazin-3(2H)-One
CAS No.	1219540-84-7
Molecular Formula	C18H14BrFN2O2
Molecular Weight	389.22 g/mol
Synonyms	6-(4-Methoxyphenyl)-2-[(4-bromo-2-fluorophenyl)methyl]-2,3-dihydropyridazin-3-one; 2-[(4-Bromo-2-fluorophenyl)methyl]-6-(4-methoxyphenyl)-3(2H)-pyridazinone; 2-(4-Bromo-2-fluorobenzyl)-6-(4-methoxyphenyl)pyridazin-3-one; 1219540-84-7; BRD-K4477; BRD K4477; BRDK4477
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromo-2-Fluorobenzyl)-6-(4-Methoxyphenyl)Pyridazin-3(2H)-One is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive (store away from light). For long-term storage, consider under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.