Description

trans-2-(2,4-Dimethoxyphenyl)Cyclopropane-1-Carboxylic Acid is a high-purity, synthetically valuable cyclopropane derivative characterized by its unique aromatic substitution pattern. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex molecules with precise stereochemistry. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or mechanical properties.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process optimization for cyclopropanation and subsequent functionalization reactions.
• Fine Chemical Production: Integral to the custom synthesis of complex, high-value organic compounds for various industrial applications.

Basic Information

Product Name	trans-2-(2,4-Dimethoxyphenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	1218647-22-3
Molecular Formula	C₁₂H₁₄O₄
Molecular Weight	222.24 g/mol
Synonyms	(1R,2S)-rel-2-(2,4-Dimethoxyphenyl)cyclopropanecarboxylic Acid; (1R,2S)-2-(2,4-Dimethoxyphenyl)cyclopropanecarboxylic Acid; trans-2-(2,4-Dimethoxyphenyl)cyclopropanecarboxylic Acid; 2-(2,4-Dimethoxyphenyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-(2,4-dimethoxyphenyl)-, trans-; (1R,2S)-2-(2,4-Dimethoxyphenyl)cyclopropane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Our trans-2-(2,4-Dimethoxyphenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.