Description

(S)-2-Benzoylthiobutyric Acid CAS NO 1217740-06-1 is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its defined stereochemistry, which is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced fine chemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop or manufacture optically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic agents, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Asymmetric Synthesis: Used as a starting material or reagent in catalytic asymmetric reactions to construct complex molecules with high enantiomeric excess.
• Agrochemical Research: Serves as a precursor in the development of enantiopure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for transition metal catalysis and organocatalysts.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Used in the manufacture of specialty chemicals where optical purity is a critical performance parameter.

Basic Information

Product Name	(S)-2-Benzoylthiobutyric Acid
CAS No.	1217740-06-1
Molecular Formula	C11H12O2S
Molecular Weight	208.27 g/mol
Synonyms	(S)-2-(Benzoylthio)butanoic Acid; (2S)-2-(Benzoylthio)butanoic Acid; (S)-2-(Benzoylsulfanyl)butyric Acid; (S)-α-(Benzoylthio)butyric Acid; (S)-2-Benzoylmercaptobutyric Acid; L-2-Benzoylthiobutyric Acid; (S)-BTA; Benzoylthiobutyric Acid (S-enantiomer)
EINECS	Contact for details

Quality Control

Our (S)-2-Benzoylthiobutyric Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm enantiomeric purity and standard methods to verify chemical identity and potency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.