Description

6-Iodoimidazo[1,2-B]Pyridazine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound is a critical intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry and drug discovery research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized to create labeled compounds or probes for studying biological pathways and target engagement.
• Material Science Research: Acts as a building block for novel organic electronic materials or metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	6-Iodoimidazo[1,2-B]Pyridazine
CAS No.	1216703-05-7
Molecular Formula	C6H4IN3
Molecular Weight	245.02 g/mol
Synonyms	6-Iodoimidazo[1,2-b]pyridazine; Imidazo[1,2-b]pyridazine, 6-iodo-; 1216703-05-7; 6-Iodo-imidazo[1,2-b]pyridazine; 6-Iodo-1H-imidazo[1,2-b]pyridazine; AI3-63535; ZINC000103259677; SCHEMBL18841427
EINECS	Contact for details

Quality Control

Every batch of 6-Iodoimidazo[1,2-B]Pyridazine is manufactured under strict quality management protocols and undergoes comprehensive analytical characterization. We ensure high purity and batch-to-batch consistency through advanced techniques like HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profile against our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.