Description

5-Chloro-3-(4-Fluorophenyl)Benzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated biphenyl structure makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated aromatic core for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its rigid, substituted biphenyl structure.
• Polymer Modifier: Employed to introduce functional carboxylic acid groups into polymer chains, enhancing properties like adhesion, solubility, or reactivity for specialty coatings and resins.
• Chemical Research & Development: A versatile scaffold in medicinal and synthetic chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Coordination Chemistry Ligand: The carboxylic acid functionality allows it to act as a ligand for metal complexes used in catalysis or material science.

Basic Information

Product Name	5-Chloro-3-(4-Fluorophenyl)Benzoic Acid
CAS No.	1214344-28-1
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	3-(4-Fluorophenyl)-5-chlorobenzoic Acid; 5-Chloro-3-(4-fluorophenyl)benzoic Acid; Benzoic acid, 5-chloro-3-(4-fluorophenyl)-; [1,1'-Biphenyl]-3-carboxylic acid, 4'-fluoro-5-chloro-; 4'-Fluoro-5-chloro[1,1'-biphenyl]-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-(4-Fluorophenyl)Benzoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.