Description

(4S)-8-Bromochromane-4-Ylamine is a chiral, brominated chromane derivative featuring a primary amine functional group. This compound is a high-value synthetic intermediate prized for its structural complexity and potential as a building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the synthesis of advanced pesticides and herbicides, leveraging the chromane scaffold for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional additive for the development of specialty polymers with unique optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A versatile building block for methodological chemistry research and the discovery of new chemical entities.

Basic Information

Product Name	(4S)-8-Bromochromane-4-Ylamine
CAS No.	1213648-96-4
Molecular Formula	C10H12BrNO
Molecular Weight	242.11 g/mol
Synonyms	8-Bromo-4-chromanamine, (4S)-; (4S)-8-Bromo-3,4-dihydro-2H-1-benzopyran-4-amine; (S)-8-Bromochroman-4-amine; 4-Chromanamine, 8-bromo-, (4S)-; (4S)-8-Bromo-3,4-dihydro-2H-chromen-4-amine; (S)-8-Bromochromane-4-amine
EINECS	Contact for details

Quality Control

Every batch of (4S)-8-Bromochromane-4-Ylamine is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.