Description

(4R)-8-Methyl-3,4-Dihydro-2H-Chromen-4-Amine is a chiral chromane derivative, a high-value building block in modern organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and fine chemicals, where its defined stereochemistry is critical for biological activity. It is needed by research institutions, pharmaceutical development labs, and fine chemical manufacturers focused on creating novel therapeutic agents, particularly in areas requiring enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of potential drug candidates, especially in central nervous system (CNS) and cardiovascular research.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development of new catalytic systems for enantioselective synthesis.
• Fine Chemical Synthesis: Serves as a building block for complex natural product analogs and specialty chemicals with specific stereochemical requirements.
• Agrochemical Development: Employed in the research and synthesis of novel, optically active crop protection agents.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(4R)-8-Methyl-3,4-Dihydro-2H-Chromen-4-Amine
CAS No.	1213065-29-2
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	(4R)-8-Methyl-3,4-dihydro-2H-1-benzopyran-4-amine; (R)-8-Methyl-3,4-dihydro-2H-chromen-4-amine; (R)-8-Methylchroman-4-amine; 4-Amino-8-methylchroman, (4R)-; 1213065-29-2; (4R)-8-Methyl-3,4-dihydro-2H-chromen-4-amine; (R)-4-Amino-8-methylchroman
EINECS	Contact for details

Quality Control

Our (4R)-8-Methyl-3,4-Dihydro-2H-Chromen-4-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.