Description

cis-2-Aminomethyl-Cyclohexylamine Dihydrochloride is a high-purity, functionalized cyclohexylamine derivative supplied as a stable dihydrochloride salt. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering a rigid cyclohexane backbone with two distinct amine functionalities. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral ligands, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis and metal complexation.
• Peptidomimetics & Bioactive Molecules: Incorporates a constrained cyclohexyl structure into peptide backbones and other bioactive compounds to modulate conformation and properties.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for specialty polymers, including polyamides and epoxy curing agents.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and herbicides.
• Chemical Research & Development: Serves as a versatile building block in academic and industrial R&D for exploring new chemical entities.

Basic Information

Product Name	cis-2-Aminomethyl-Cyclohexylamine Dihydrochloride
CAS No.	1212366-42-1
Molecular Formula	C7H18N2·2HCl
Molecular Weight	215.15 g/mol
Synonyms	(1R,2S)-2-(Aminomethyl)cyclohexanamine dihydrochloride; (1S,2R)-2-(Aminomethyl)cyclohexanamine dihydrochloride; cis-2-(Aminomethyl)cyclohexylamine dihydrochloride; 2-(Aminomethyl)cyclohexanamine dihydrochloride (cis-); (1R,2S)-rel-2-(Aminomethyl)cyclohexanamine dihydrochloride; Cyclohexanamine, 2-(aminomethyl)-, dihydrochloride, cis-; AMCHA dihydrochloride (cis-)
EINECS	Contact for details

Quality Control

Our cis-2-Aminomethyl-Cyclohexylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (cis- isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.