Description

5-(Trifluoromethyl)Pyridazin-3-Amine is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique trifluoromethylpyridazine core offers significant potential for modulating the physicochemical properties of target molecules, particularly in enhancing metabolic stability and lipophilicity. Pharmaceutical, agrochemical, and material science researchers need it for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic systems.
• Chemical Biology Probe Development: Employed in designing molecular probes and tags for studying biological processes due to its distinct structural motif.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Fundamental research reagent in heterocyclic and fluorine chemistry for exploring new reaction pathways and compound libraries.

Basic Information

Product Name	5-(Trifluoromethyl)Pyridazin-3-Amine
CAS No.	1211591-88-6
Molecular Formula	C5H4F3N3
Molecular Weight	163.10 g/mol
Synonyms	3-Amino-5-(trifluoromethyl)pyridazine; 5-(Trifluoromethyl)-3-pyridazinamine; 5-Trifluoromethylpyridazin-3-ylamine; 3-Pyridazinamine, 5-(trifluoromethyl)-; 1211591-88-6; 5-Trifluoromethyl-3-aminopyridazine; 5-CF3-Pyridazin-3-amine
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Pyridazin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with custom purity grades and analytical method development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.