Description

2-Bromo-3-Methylisonicotinic Acid is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized isonicotinic acid scaffold, enabling the introduction of both bromine and methyl groups for precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors or other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogenated pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional organic materials and metal-organic frameworks (MOFs) due to its carboxylic acid and halogen functionalities.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	2-Bromo-3-Methylisonicotinic Acid
CAS No.	1211583-05-9
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	3-Methyl-2-bromoisonicotinic acid; 2-Bromo-3-methyl-4-pyridinecarboxylic acid; 4-Pyridinecarboxylic acid, 2-bromo-3-methyl-; Isonicotinic acid, 2-bromo-3-methyl-; 2-Bromo-3-methylpyridine-4-carboxylic acid; 3-Methyl-2-bromopyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methylisonicotinic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with global regulatory frameworks, and specifications can be aligned with cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.