Description

(1R,2S,3S,4R,5R)-5-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl)-1-(Hydroxymethyl)-6,8-Dioxabicyclo[3.2.1]Octane-2,3,4-Triol is a high-purity, complex bicyclic organic compound with significant potential as a key intermediate in advanced pharmaceutical synthesis. This molecule is valued for its precise stereochemistry and functional groups, which make it a versatile building block for developing novel therapeutic agents. It is primarily targeted at research institutions and pharmaceutical companies engaged in the discovery and development of new drugs, particularly in areas requiring sophisticated chiral scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or metabolic disorder targets.
• Medicinal Chemistry Research: Used in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization due to its complex, polyfunctional structure.
• Process Chemistry Development: Employed in scaling up synthetic routes for candidate drugs, requiring high chemical and isomeric purity.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Probe Development: Potential use in creating tool compounds for investigating biological pathways and enzyme inhibition.

Basic Information

Product Name	(1R,2S,3S,4R,5R)-5-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl)-1-(Hydroxymethyl)-6,8-Dioxabicyclo[3.2.1]Octane-2,3,4-Triol
CAS No.	1210344-30-1
Molecular Formula	C24H27ClO7
Molecular Weight	462.92 g/mol
Synonyms	5-(4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol; Relacorilant Impurity; CORT 125134 Impurity; (1R,2S,3S,4R,5R)-5-[4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol; Bicyclo[3.2.1]octane-2,3,4-triol derivative; GR Antagonist Intermediate; Selective Glucocorticoid Receptor Modulator Intermediate
EINECS	Contact for details

Quality Control

Every batch of (1R,2S,3S,4R,5R)-5-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl)-1-(Hydroxymethyl)-6,8-Dioxabicyclo[3.2.1]Octane-2,3,4-Triol is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.