Description

[(R)-(+)-5,5'-Bis(Diphenylphosphino)-4,4'-Bi-1,3-Benzodioxole][4-Cyano-3-Nitrobenzenecarboxylato][1,2,3-η-2-Propenylir(Iii) is a sophisticated, chiral organometallic complex designed for high-performance asymmetric catalysis. This compound matters because it provides exceptional stereoselectivity and catalytic activity, enabling the efficient synthesis of complex, single-enantiomer molecules. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for creating novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical synthesis.
• Pharmaceutical Intermediate Production: Enables the creation of chiral building blocks for APIs targeting central nervous system, cardiovascular, and oncological diseases.
• Fine Chemical Synthesis: Used in the production of high-value specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & Industrial R&D: Serves as a critical reagent for developing new catalytic methodologies and exploring novel reaction pathways.
• Process Chemistry Optimization: Employed to scale up and optimize manufacturing routes for chiral compounds, improving yield and purity.
• Ligand Screening & Catalyst Development: Acts as a benchmark or precursor complex in the discovery of new chiral phosphine-based catalyst systems.

Basic Information

Product Name	[(R)-(+)-5,5'-Bis(Diphenylphosphino)-4,4'-Bi-1,3-Benzodioxole][4-Cyano-3-Nitrobenzenecarboxylato][1,2,3-η-2-Propenylir(Iii)
CAS No.	1208092-27-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(R)-SEGPHOS Iridium(III) Allyl Complex; (R)-(+)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole (4-cyano-3-nitrobenzoato-κO)(η3-2-propenyl)iridium; Iridium(III) allyl complex with (R)-SEGPHOS and 4-cyano-3-nitrobenzoate; Asymmetric hydrogenation catalyst precursor; Chiral iridium-phosphine complex; (R)-DTBM-SEGPHOS Ir(allyl) complex derivative
EINECS	Contact for details

Quality Control

Our high-purity organometallic catalysts are produced and handled under strict inert atmosphere conditions to ensure stability and performance. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess. Certificates of Analysis (COA) detailing identity, purity, and specific tests are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Chiral Purity (Chiral HPLC)	≥ 99% e.e.
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.