Description

2H-Pyran-4-Propanoic Acid, α-Aminotetrahydro-, Hydrochloride (1:1), (αr)- is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a defined stereocenter for precise chemical transformations. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients. The product is supplied as a hydrochloride salt to enhance its stability and handling properties.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs.
• Agrochemical Synthesis: Building block for creating advanced, enantiomerically pure pesticides and herbicides.
• Chemical Research: Used in academic and industrial R&D for methodological studies in asymmetric synthesis and medicinal chemistry.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing processes.
• Ligand & Catalyst Development: Potential precursor for designing novel chiral ligands and organocatalysts.

Basic Information

Item	Detail
Product Name	2H-Pyran-4-Propanoic Acid, α-Aminotetrahydro-, Hydrochloride (1:1), (αr)-
CAS No.	1207447-38-8
Molecular Formula	C8H15NO3 • HCl
Molecular Weight	209.67 g/mol (Free base: 173.21 g/mol)
Synonyms	(αR)-α-Aminotetrahydro-2H-pyran-4-propanoic acid hydrochloride; (R)-3-Amino-3-(tetrahydro-2H-pyran-4-yl)propanoic acid hydrochloride; Tetrahydro-2H-pyran-4-propanoic acid, α-amino-, hydrochloride, (αR)-; AR-THP-Pro-OH•HCl; (R)-Aminotetrahydropyran-4-ylpropionic acid HCl
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-4-Propanoic Acid, α-Aminotetrahydro-, Hydrochloride (1:1), (αr)- is produced under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting customer and research standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.