Description

2H-Pyran-4-Propanoic Acid, α-Aminotetrahydro-, (αr)- is a chiral, non-proteinogenic amino acid derivative featuring a tetrahydro-2H-pyran ring system. This compound matters as a sophisticated building block for the synthesis of complex molecules, offering a unique scaffold for introducing both amino and carboxylic acid functionalities in a constrained, heterocyclic framework. Pharmaceutical and agrochemical research organizations need it for developing novel active ingredients, particularly in medicinal chemistry for creating peptidomimetics and other bioactive compounds.

Application

• As a key chiral intermediate in the synthesis of pharmaceutical candidates, especially for protease inhibitors and GPCR-targeted therapies.
• Utilized in medicinal chemistry for the construction of peptidomimetic scaffolds to improve metabolic stability and bioavailability.
• Acts as a specialized building block in organic synthesis for creating libraries of compounds in drug discovery programs.
• Potential use in the development of agrochemicals, such as novel herbicides or fungicides with specific modes of action.
• Employed in academic and institutional research exploring new chemical spaces and reaction methodologies.
• Serves as a precursor for ligand synthesis in catalysis and materials science applications.

Basic Information

Product Name	2H-Pyran-4-Propanoic Acid, α-Aminotetrahydro-, (αr)-
CAS No.	1207447-36-6
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	(αR)-α-Aminotetrahydro-2H-pyran-4-propanoic Acid; (R)-3-(4-Aminotetrahydro-2H-pyran-4-yl)propanoic Acid; 4-(2-Carboxyethyl)-4-aminotetrahydro-2H-pyran; (R)-4-(2-Carboxyethyl)-4-aminotetrahydropyran; (R)-3-(4-Aminooxan-4-yl)propanoic Acid; 4-Amino-4-(2-carboxyethyl)tetrahydro-2H-pyran; AR-Aminotetrahydro-2H-pyran-4-propanoic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity (enantiomeric excess), chemical purity, and residual solvent content. We adhere to a cGMP-compliant quality management system for products intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.