Description

Spiro[2H-1-Benzopyran-2,4'-Piperidine]-1'-Carboxylic Acid, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable and consistent supply of complex building blocks for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential therapeutic agents, particularly for neurological and psychiatric conditions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Biology Probe Development: Serves as a core scaffold for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, non-commercial compounds for client R&D.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Spiro[2H-1-Benzopyran-2,4'-Piperidine]-1'-Carboxylic Acid, 1,1-Dimethylethyl Ester
CAS No.	1207163-67-4
Molecular Formula	C19H25NO3
Molecular Weight	315.41 g/mol
Synonyms	tert-Butyl Spiro[2H-1-Benzopyran-2,4'-Piperidine]-1'-Carboxylate; 1'-BOC-Spiro[Chromene-2,4'-Piperidine]; 1,1-Dimethylethyl Spiro[2H-1-Benzopyran-2,4'-piperidine]-1'-carboxylate; 1'-tert-Butoxycarbonylspiro[chromene-2,4'-piperidine]; BOC-Spiro(Chromene-2,4'-Piperidine); Spiro[Chromene-2,4'-piperidine]-1'-carboxylic acid tert-butyl ester; 1'-BOC-1,2-Dihydrospiro[3,1-benzoxazine-4,4'-piperidine]
EINECS	Contact for details

Quality Control

Our Spiro[2H-1-Benzopyran-2,4'-Piperidine]-1'-Carboxylic Acid, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.