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tert-Butyl 2,2-Dimethyl-5-(6-Phenoxynaphthalen-2-Yl)-1,3-Dioxan-5-Ylcarbamate CAS NO 1206676-76-7


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CAS No.:1206676-76-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

tert-Butyl 2,2-Dimethyl-5-(6-Phenoxynaphthalen-2-Yl)-1,3-Dioxan-5-Ylcarbamate is a sophisticated, high-purity chemical intermediate designed for advanced synthesis. This compound is critical for research and development in pharmaceutical chemistry, offering a protected carbamate and dioxane scaffold for constructing complex molecules. It is primarily utilized by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
  • Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
  • Process Chemistry Development: Employed in route scouting and scale-up processes for the manufacture of target molecules.
  • Organic Synthesis: Acts as a versatile intermediate for constructing molecules containing naphthalene and phenoxy motifs.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for proprietary synthesis projects.

Basic Information

Product Name tert-Butyl 2,2-Dimethyl-5-(6-Phenoxynaphthalen-2-Yl)-1,3-Dioxan-5-Ylcarbamate
CAS No. 1206676-76-7
Molecular Formula C27H31NO5
Molecular Weight 449.54 g/mol
Synonyms Boc-Protected Amino Dioxane Naphthalene Derivative; 5-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-(6-phenoxy-2-naphthalenyl)-2,2-dimethyl-1,3-dioxane; tert-Butyl N-[5-(6-phenoxynaphthalen-2-yl)-2,2-dimethyl-1,3-dioxan-5-yl]carbamate; 1,3-Dioxane-5-carboxamide, 5-(6-phenoxy-2-naphthalenyl)-2,2-dimethyl-, 1,1-dimethylethyl ester; CAS 1206676-76-7
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Quality Control

Our tert-Butyl 2,2-Dimethyl-5-(6-Phenoxynaphthalen-2-Yl)-1,3-Dioxan-5-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC/MS) Conforms
Identification (NMR) Conforms
Assay (HPLC) ≥97.0%
Purity (HPLC, Area%) ≥98.0%
Single Unknown Impurity ≤1.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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