Description

3-Iodo-6-(Trifluoromethyl)Pyridazine is a high-value, halogenated pyridazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, combining an iodine substituent with a trifluoromethyl group on a pyridazine ring, enabling precise structural modifications and introducing desirable physicochemical properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, leveraging the stability and lipophilicity imparted by the trifluoromethyl group.
• Material Science Precursor: Serves as a building block for creating specialized ligands, functionalized polymers, and liquid crystal materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Fluorine Chemistry: Acts as a valuable reagent in fluorine chemistry research for introducing the CF3 moiety into more complex molecular frameworks.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	3-Iodo-6-(Trifluoromethyl)Pyridazine
CAS No.	1206524-33-5
Molecular Formula	C5H2F3IN2
Molecular Weight	273.98 g/mol
Synonyms	6-(Trifluoromethyl)-3-iodopyridazine; 3-Iodo-6-trifluoromethylpyridazine; Pyridazine, 3-iodo-6-(trifluoromethyl)-; 1206524-33-5; 3-Iodo-6-(trifluoromethyl)-1,2-diazine
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-(Trifluoromethyl)Pyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.