Description

2-Tributylstannyl-3-Trifluoromethylpyridine is a high-value organotin reagent featuring a pyridine ring substituted with a trifluoromethyl group and a tributylstannyl moiety. This compound is a critical building block in modern synthetic chemistry, enabling efficient cross-coupling reactions for the construction of complex molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in Stille cross-coupling reactions for the synthesis of complex heterocyclic compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized organic materials, including ligands for catalysis and monomers for specialty polymers.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Catalyst Ligand Development: The pyridine-stannane structure can be utilized to develop novel organometallic catalysts for various transformation reactions.

Basic Information

Product Name	2-Tributylstannyl-3-Trifluoromethylpyridine
CAS No.	1204580-78-8
Molecular Formula	C18H30F3NSn
Molecular Weight	428.14 g/mol
Synonyms	3-Trifluoromethyl-2-(tributylstannyl)pyridine; 2-(Tributylstannyl)-3-(trifluoromethyl)pyridine; Tributyl(3-trifluoromethyl-2-pyridyl)stannane; 2-Tributyltin-3-trifluoromethylpyridine; 2-Pyridinestannane, 3-(trifluoromethyl)-, tributyl-; 2-Stannyl-3-trifluoromethylpyridine, tributyl-
EINECS	Contact for details

Quality Control

Our 2-Tributylstannyl-3-Trifluoromethylpyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity and assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Tin (Sn) Content	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.