Description

5-Tributylstannyl-2-Trifluoromethylpyridine is a high-value organotin intermediate featuring a reactive tributylstannyl group and a stable trifluoromethylpyridine backbone. This compound matters for its critical role in facilitating efficient cross-coupling reactions, particularly Stille couplings, enabling the synthesis of complex molecules in pharmaceutical and advanced material research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) via Stille cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides requiring the introduction of pyridine and fluorinated motifs.
• Material Science Research: Serves as a precursor for creating functionalized organic semiconductors and ligands for catalysis.
• Organic Synthesis: Enables the efficient formation of carbon-carbon bonds in complex molecule construction for academic and industrial research.
• Fluorinated Compound Libraries: Essential for medicinal chemistry programs focused on exploring the benefits of fluorine substitution in drug candidates.

Basic Information

Product Name	5-Tributylstannyl-2-Trifluoromethylpyridine
CAS No.	1204580-76-6
Molecular Formula	C18H30F3NSn
Molecular Weight	440.14 g/mol
Synonyms	2-(Trifluoromethyl)-5-(tributylstannyl)pyridine; 5-(Tributylstannyl)-2-(trifluoromethyl)pyridine; Tributyl(2-(trifluoromethyl)pyridin-5-yl)stannane; 2-Trifluoromethyl-5-tributylstannylpyridine; Pyridine, 5-(tributylstannyl)-2-(trifluoromethyl)-; Stannane, tributyl[2-(trifluoromethyl)-5-pyridinyl]-
EINECS	Contact for details

Quality Control

Our 5-Tributylstannyl-2-Trifluoromethylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	26.5 - 27.5 %
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.