Description

2,3-Difluoro-4-(Tributylstannyl)Pyridine is a high-value organotin reagent and a key pyridine derivative used in advanced organic synthesis. This compound matters as a versatile building block for constructing complex molecules, particularly through cross-coupling reactions like the Stille reaction. Pharmaceutical, agrochemical, and advanced materials researchers need it for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing difluoropyridine motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atoms and tin moiety enable precise structural modifications.
• Material Science Research: Serves as a building block for creating specialized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions (Stille Coupling): The tributylstannyl group makes it an excellent partner for palladium-catalyzed cross-coupling with aryl or vinyl halides, enabling efficient carbon-carbon bond formation.
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of molecular probes, fluorinated analogs of bioactive compounds, and for late-stage functionalization strategies.
• Catalyst & Ligand Development: Used to synthesize novel organometallic complexes and catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2,3-Difluoro-4-(Tributylstannyl)Pyridine
CAS No.	1204580-71-1
Molecular Formula	C17H29F2NSn
Molecular Weight	404.12 g/mol
Synonyms	4-(Tributylstannyl)-2,3-difluoropyridine; Tributyl(2,3-difluoro-4-pyridinyl)stannane; 2,3-Difluoro-4-(tributylstannyl)pyridine; 2,3-Difluoro-4-pyridyltributyltin; Stannane, tributyl(2,3-difluoro-4-pyridinyl)-; 2,3-Difluoro-4-tributylstannylpyridine
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-(Tributylstannyl)Pyridine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Tin (Sn) Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.