Description

1,4,7,10-Benzotetraoxacyclododecin-12-Carboxylic Acid, 13-Amino-2,3,5,6,8,9-Hexahydro-, Ethyl Ester is a sophisticated macrocyclic compound featuring a benzotetraoxacyclododecin core structure, functionalized with both amino and ester groups. This unique molecular architecture makes it a valuable advanced intermediate or building block for the synthesis of complex molecules in high-value research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for applications in drug discovery, ligand synthesis, and the development of specialty polymers.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and neurological disorder research.
• Ligand Synthesis: Used in the development of complex chelating agents and macrocyclic ligands for catalysis and metal ion sequestration.
• Agrochemical Research: Serves as a precursor in the design and synthesis of new-generation herbicides, fungicides, or plant growth regulators.
• Material Science: A monomer or cross-linking agent for creating specialty polymers with specific thermal, mechanical, or optical properties.
• Chemical Biology Probe: Utilized in the construction of molecular probes for studying biological processes and target identification.
• Supramolecular Chemistry: Acts as a core structure for constructing host-guest complexes and molecular recognition systems.

Basic Information

Item	Details
Product Name	1,4,7,10-Benzotetraoxacyclododecin-12-Carboxylic Acid, 13-Amino-2,3,5,6,8,9-Hexahydro-, Ethyl Ester
CAS No.	1204386-13-9
Molecular Formula	C₁₇H₂₃NO₇
Molecular Weight	353.37 g/mol
Synonyms	Ethyl 13-amino-2,3,5,6,8,9-hexahydro-1,4,7,10-benzotetraoxacyclododecine-12-carboxylate; 13-Amino-2,3,5,6,8,9-hexahydro-1,4,7,10-benzotetraoxacyclododecin-12-carboxylic acid ethyl ester; Amino-functionalized benzocrown ether ethyl ester; Benzocrown ether amino acid ester; CAS 1204386-13-9
EINECS	Contact for details

Quality Control

Our high-purity chemical intermediates are manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.