Description

tert-Butyl n-(2,2-Difluoroethyl)Carbamate is a specialized organic building block used in advanced chemical synthesis. This compound is valued for its role as a protected amine intermediate, enabling the controlled introduction of the 2,2-difluoroethylamine moiety into complex molecules. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical and agrochemical industries for the production of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a difluoroethylamine functional group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoro motif can enhance biological activity.
• Peptide Mimetics & PROTACs: Serves as a crucial component in the development of peptide analogs and proteolysis-targeting chimeras (PROTACs) for drug discovery.
• Material Science Research: Employed in the creation of novel fluorinated polymers and specialty materials with unique properties.
• Chemical Biology Probes: Utilized as a reagent for labeling and modifying biomolecules in diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for custom synthesis projects and scale-up processes.

Basic Information

Product Name	tert-Butyl n-(2,2-Difluoroethyl)Carbamate
CAS No.	1204333-50-5
Molecular Formula	C7H13F2NO2
Molecular Weight	181.18 g/mol
Synonyms	Boc-2,2-Difluoroethylamine; N-Boc-2,2-Difluoroethylamine; tert-Butyl (2,2-difluoroethyl)carbamate; 2,2-Difluoroethylcarbamic Acid tert-Butyl Ester; 1,1-Dimethylethyl N-(2,2-difluoroethyl)carbamate; (2,2-Difluoroethyl)carbamic Acid 1,1-Dimethylethyl Ester; N-(tert-Butoxycarbonyl)-2,2-difluoroethylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(2,2-Difluoroethyl)Carbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.