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(2R,5R)-1-{[(2R,5R)-2,5-Dimethylpyrrolidin-1-Yl]Methylene}-2,5-Dimethylpyrrolidinium Tetrafluoroborate, Min. 97% CAS NO 1204324-14-0


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CAS No.:1204324-14-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2R,5R)-1-{[(2R,5R)-2,5-Dimethylpyrrolidin-1-Yl]Methylene}-2,5-Dimethylpyrrolidinium Tetrafluoroborate, Min. 97% is a high-purity, chiral pyrrolidinium salt with a defined stereochemistry, serving as a sophisticated building block and catalyst in advanced organic synthesis. Its value lies in its role as a highly selective organocatalyst or chiral phase-transfer catalyst, enabling the production of enantiomerically pure compounds critical for modern pharmaceuticals and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereocontrol in asymmetric synthesis.

Application

  • Asymmetric Synthesis: As a chiral phase-transfer catalyst (PTC) or organocatalyst for enantioselective alkylation, Michael addition, and other C-C bond-forming reactions.
  • Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity, particularly in neurology and oncology drug candidates.
  • Agrochemical Research: Used in the development of chiral herbicides, fungicides, and pesticides where biological activity is stereospecific.
  • Ligand Precursor: Serves as a precursor for the synthesis of chiral ligands used in transition metal catalysis.
  • Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process optimization in pilot plants.
  • Fine Chemical Production: Enables the manufacture of high-value chiral flavors, fragrances, and electronic chemicals.

Basic Information

Item Detail
Product Name (2R,5R)-1-{[(2R,5R)-2,5-Dimethylpyrrolidin-1-Yl]Methylene}-2,5-Dimethylpyrrolidinium Tetrafluoroborate, Min. 97%
CAS No. 1204324-14-0
Molecular Formula C14H26N2·BF4
Molecular Weight 300.18 g/mol
Synonyms (2R,5R)-2,5-Dimethyl-1-[(2R,5R)-2,5-dimethyl-1-pyrrolidinylmethylene]pyrrolidinium Tetrafluoroborate; Chiral Dimethylpyrrolidinium Tetrafluoroborate; (R,R)-Pyrrolidinium PTC; (2R,5R)-DMPT Tetrafluoroborate; Asymmetric Pyrrolidinium Salt; (R,R)-1-[(R,R)-2,5-Dimethylpyrrolidin-1-ylmethylene]-2,5-dimethylpyrrolidinium Tetrafluoroborate
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and chiral integrity using advanced analytical techniques. Certificates of Analysis (COA) detailing assay, enantiomeric excess (ee), and impurity profiles are available upon request. Our quality system is designed to meet the stringent requirements of cGMP and ISO guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider handling under an inert atmosphere such as nitrogen or argon to maintain product integrity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) Min. 97.0%
Enantiomeric Excess (Chiral HPLC) Min. 99.0% ee
Water Content (KF) Max. 0.5%
Residue on Ignition Max. 0.1%
Heavy Metals (as Pb) Max. 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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