Description

5-Chloro-4-Chromanone is a versatile organic intermediate characterized by its chromanone core structure substituted with a chlorine atom. This compound matters as a key building block in synthetic organic chemistry, enabling the construction of complex molecules for advanced material and pharmaceutical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its halogenated structure for bioactive molecule design.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a starting material for synthesizing advanced electron-transport or host materials in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the preparation of specialized chiral ligands and organocatalysts for asymmetric synthesis.
• Flavor and Fragrance Chemistry: Acts as an intermediate for creating complex aroma chemicals and synthetic flavors.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic synthesis, including cyclization and functionalization reactions.

Basic Information

Product Name	5-Chloro-4-Chromanone
CAS No.	1199782-82-5
Molecular Formula	C9H7ClO2
Molecular Weight	182.60 g/mol
Synonyms	5-Chloro-4-chromanone; 5-Chloro-4H-chromen-4-one; 5-Chloro-4-oxo-4H-chromene; 4H-1-Benzopyran-4-one, 5-chloro-; 5-Chlorochroman-4-one; 5-Chloro-4-chromone
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Chromanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.