Description

(E)-n-[(5-Fluoropyridin-3-Yl)Methylidene]Hydroxylamine is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluoropyridine moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex heterocyclic compounds.
• Fluorinated Building Block: Provides a strategic point for introducing fluorine atoms into target molecules to modulate their physicochemical and pharmacokinetic properties.

Basic Information

Product Name	(E)-n-[(5-Fluoropyridin-3-Yl)Methylidene]Hydroxylamine
CAS No.	1198353-49-9
Molecular Formula	C7H6FN2O
Molecular Weight	153.13 g/mol
Synonyms	(E)-N-[(5-Fluoropyridin-3-yl)methylene]hydroxylamine; 5-Fluoro-3-[(E)-(hydroxyimino)methyl]pyridine; (E)-5-Fluoro-3-pyridinecarboxaldehyde oxime; (E)-O-(5-Fluoropyridin-3-ylmethylene)hydroxylamine; 3-Pyridinecarboxaldehyde, 5-fluoro-, oxime; (E)-Isomer of 5-Fluoro-3-pyridinealdoxime
EINECS	Contact for details

Quality Control

Our (E)-n-[(5-Fluoropyridin-3-Yl)Methylidene]Hydroxylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and other fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.