Description

6-(Cbz-Amino)-3-Pyridazinecarboxylic Acid CAS NO 1197193-41-1 is a high-purity, protected amino acid derivative specifically designed for advanced pharmaceutical research and synthesis. This compound serves as a critical key building block in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily utilized by research scientists and process chemists in pharmaceutical, biotechnology, and fine chemical industries for peptide coupling, medicinal chemistry, and the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative for constructing specific peptide sequences.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes to introduce the pyridazine-carboxylic acid pharmacophore.
• Chemical Biology: Acts as a building block for creating chemical probes and labeled compounds used in biochemical assays and target identification.
• Fine Chemical Synthesis: Serves as a precursor for the synthesis of more complex heterocyclic compounds and specialty chemicals.
• Contract Research & Manufacturing (CRMO): Supplied to organizations engaged in custom synthesis and scale-up services for clinical trial materials.

Basic Information

Product Name	6-(Cbz-Amino)-3-Pyridazinecarboxylic Acid
CAS No.	1197193-41-1
Molecular Formula	C14H13N3O4
Molecular Weight	287.27 g/mol
Synonyms	6-[(Benzyloxycarbonyl)amino]pyridazine-3-carboxylic acid; 6-(N-Cbz-Amino)-3-pyridazinecarboxylic Acid; 6-[(Benzyloxycarbonyl)amino]-3-pyridazinecarboxylic acid; 3-Pyridazinecarboxylic acid, 6-[[(phenylmethoxy)carbonyl]amino]-; Z-6-Amino-3-pyridazinecarboxylic Acid; Cbz-6-Amino-3-pyridazinecarboxylic Acid; N-Carbobenzoxy-6-amino-3-pyridazinecarboxylic Acid; 6-Amino-3-pyridazinecarboxylic acid N-benzyloxycarbonyl derivative
EINECS	Contact for details

Quality Control

Our 6-(Cbz-Amino)-3-Pyridazinecarboxylic Acid is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.