Description

7-Chloro-2H-Pyrano[2,3-B]Pyridin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant interest in modern organic synthesis. Its core value lies in its fused pyrano-pyridinone scaffold, which serves as a privileged structure for developing novel bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly those focused on creating new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used as a building block for developing new generations of herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or functional unit in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic chemistry and medicinal chemistry.
• Fine Chemical Synthesis: Employed in multi-step syntheses to construct complex, high-value molecules for specialty chemical applications.

Basic Information

Product Name	7-Chloro-2H-Pyrano[2,3-B]Pyridin-4(3H)-One
CAS No.	1196145-79-5
Molecular Formula	C8H4ClNO2
Molecular Weight	181.58 g/mol
Synonyms	7-Chloro-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-one; 7-Chloro-4-oxo-3,4-dihydro-2H-pyrano[2,3-b]pyridine; 7-Chloro-2H-pyrano[2,3-b]pyridin-4(3H)-one; 7-Chloro-3,4-dihydro-2H,4H-pyrano[2,3-b]pyridin-4-one; 7-Chloro-4H-pyrano[2,3-b]pyridin-4-one, 1,2-dihydro-; 1196145-79-5
EINECS	Contact for details

Quality Control

Our 7-Chloro-2H-Pyrano[2,3-B]Pyridin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.