Description

[4-(3-Bromophenyl)Oxan-4-Yl]Methanaminehydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated phenyl-tetrahydropyran structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents, kinase inhibitors, and other therapeutic small molecules. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for neurological and oncological targets.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Used in organic synthesis to introduce the functionalized tetrahydropyranyl-methanamine moiety into more complex molecular architectures.
• Process Chemistry & Scale-Up: Supports process development and pilot-scale manufacturing of APIs requiring this specific bromophenyl-substituted intermediate.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical development pipelines.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	[4-(3-Bromophenyl)Oxan-4-Yl]Methanaminehydrochloride
CAS No.	1193388-26-9
Molecular Formula	C12H17BrClNO
Molecular Weight	306.63 g/mol
Synonyms	(4-(3-Bromophenyl)tetrahydro-2H-pyran-4-yl)methanamine hydrochloride; 1-(4-(3-Bromophenyl)tetrahydro-2H-pyran-4-yl)methanamine HCl; 4-(3-Bromophenyl)tetrahydropyran-4-ylmethanamine hydrochloride; (4-(3-Bromophenyl)tetrahydro-2H-pyran-4-yl)methylamine hydrochloride; 4-(3-Bromophenyl)-4-(aminomethyl)tetrahydro-2H-pyran hydrochloride; Bromophenyl-tetrahydropyranyl-methanamine HCl; 1193388-26-9 (CAS)
EINECS	Contact for details

Quality Control

Our [4-(3-Bromophenyl)Oxan-4-Yl]Methanaminehydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with the standards required for cGMP and non-GMP research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.