Description

4-Chloro-Pyridazine Hydrochloride is a versatile halogenated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in providing a reactive chlorinated pyridazine scaffold, enabling the efficient synthesis of complex molecules for pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists engaged in creating novel active ingredients, particularly in the development of kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies and central nervous system (CNS) drugs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridazine core's bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile handle for creating molecular probes, enzyme inhibitors, and tool compounds for biological target validation.
• Material Science: Employed in the synthesis of advanced organic materials, including ligands for catalysis and components for organic electronics.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) settings.
• Academic & Discovery Chemistry: Fundamental research reagent for exploring new chemical reactions and constructing diverse heterocyclic libraries.

Basic Information

Product Name	4-Chloro-Pyridazine Hydrochloride
CAS No.	1193386-63-8
Molecular Formula	C4H4Cl2N2
Molecular Weight	151.00 g/mol
Synonyms	4-Chloropyridazine Hydrochloride; 4-Chloro-1,2-diazine Hydrochloride; Pyridazine, 4-chloro-, hydrochloride (1:1); 4-Chloro-1,2-diazinium Chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-Pyridazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.