Description

3-Chloro-4-(Difluoromethoxy)Benzoic Acid is a high-purity, synthetically valuable benzoic acid derivative distinguished by its chloro and difluoromethoxy substituents. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the development of novel active ingredients. It is primarily required by R&D laboratories and manufacturing units in the pharmaceutical, agrochemical, and specialty chemical sectors for the production of complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting metabolic and inflammatory pathways.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides and pesticides, leveraging the stability imparted by the fluorine atoms.
• Liquid Crystal & OLED Material Research: Serves as a starting material for creating fluorinated aromatic compounds used in electronic display technologies.
• Organic Ligand Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the production of client-specific, fluorinated fine chemicals.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and novel synthetic methodology development.

Basic Information

Product Name	3-Chloro-4-(Difluoromethoxy)Benzoic Acid
CAS No.	1192829-74-5
Molecular Formula	C8H5ClF2O3
Molecular Weight	222.57 g/mol
Synonyms	3-Chloro-4-(difluoromethoxy)benzoic acid; Benzoic acid, 3-chloro-4-(difluoromethoxy)-; 4-(Difluoromethoxy)-3-chlorobenzoic acid; 3-Chloro-4-difluoromethoxybenzoic acid; 1192829-74-5; CAS 1192829-74-5
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Difluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality commitment supports compliance with cGMP and ISO guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.