Description

(S)-Dtb-Siphox-Ir CAS NO 1192772-21-6 is a specialized, chiral organometallic ligand based on a phosphine-oxazoline (PHOX) scaffold, designed for asymmetric catalysis. Its primary value lies in enabling highly enantioselective transformations, particularly in iridium-catalyzed hydrogenation reactions, which are critical for producing single-enantiomer intermediates. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries who require precise stereochemical control for synthesizing active pharmaceutical ingredients (APIs) and advanced chiral molecules.

Application

• As a chiral ligand for iridium-catalyzed asymmetric hydrogenation of olefins, ketones, and imines.
• Key component in the synthesis of enantiomerically pure pharmaceutical intermediates and active ingredients.
• Catalyst development for fine chemical and agrochemical production requiring high stereoselectivity.
• Academic and industrial research in developing new asymmetric catalytic methodologies.
• Use in tandem or sequential catalytic processes for complex molecule construction.
• Potential application in material science for creating chiral surfaces or polymers.

Basic Information

Product Name	(S)-Dtb-Siphox-Ir
CAS No.	1192772-21-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(S)-DTB-SIPHOX-Ir; (S)-5,5'-Di-tert-butyl-2,2'-bis(4,5-dihydrooxazole); (S)-DTB-SIPHOX Iridium complex; (S)-DTB-SIPHOX ligand; Chiral PHOX-Ir catalyst; (S)-Di-tert-butyl-SIPHOX-Ir; Asymmetric hydrogenation ligand 1192772-21-6; Iridium-(S)-DTB-SIPHOX
EINECS	Contact for details

Quality Control

Our (S)-Dtb-Siphox-Ir is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analysis, including chiral purity verification and metal content assay, to meet the stringent requirements of process chemistry and API synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling and packaging should minimize exposure to light to maintain catalytic activity and stability.

Specification

Item	Specification
Appearance	Solid (color to be specified)
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (typical)
Chiral Purity (Chiral HPLC)	≥99% ee (typical)
Iridium Content	To be specified
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.