Description

Glycocholic Acid Hydrate Synthetic is a high-purity, synthetically produced bile acid derivative. This compound serves as a critical biochemical reagent and pharmaceutical intermediate, valued for its defined structure and consistent quality. It is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors who require reliable, high-grade materials for advanced applications.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel therapeutic agents and drug delivery systems targeting liver and metabolic functions.
• Biochemical Research: Acts as a key reagent in studies of bile acid metabolism, membrane transport, and receptor interaction (e.g., FXR, TGR5).
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and components for clinical diagnostic kits, particularly liver function tests.
• Cell Culture & Microbiology: Utilized as a supplement in specialized cell culture media to facilitate the solubilization of lipids and fat-soluble vitamins.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and food analysis laboratories.

Basic Information

Product Name	Glycocholic Acid Hydrate Synthetic
CAS No.	1192657-83-2
Molecular Formula	C₂₆H₄₃NO₆ • xH₂O
Molecular Weight	465.63 g/mol (anhydrous basis)
Synonyms	Glycocholic Acid Monohydrate; N-[(3α,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]glycine Hydrate; Tauroglycocholic Acid (related); Cholylglycine Hydrate; GCA Hydrate; 3α,7α,12α-Trihydroxy-5β-cholan-24-oylglycine Hydrate; Glycocholate Hydrate
EINECS	Contact for details

Quality Control

Our Glycocholic Acid Hydrate Synthetic is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.