Description

Ethyl 3-Hydroxy-8,9-Dihydro-5H-Pyridazino[3,4-D]Azepine-7(6H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its potential role as a key building block in novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Employed in process chemistry for the development and scale-up of new active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays to study specific enzyme or receptor interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.
• Academic Research: Utilized in university and institutional laboratories for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Item	Detail
Product Name	Ethyl 3-Hydroxy-8,9-Dihydro-5H-Pyridazino[3,4-D]Azepine-7(6H)-Carboxylate
CAS No.	1190897-26-7
Molecular Formula	C12H15N3O3
Molecular Weight	249.27 g/mol
Synonyms	Ethyl 3-hydroxy-6,7,8,9-tetrahydro-5H-pyridazino[3,4-d]azepine-7-carboxylate; 7H-Pyridazino[3,4-d]azepine-7-carboxylic acid, 8,9-dihydro-3-hydroxy-5H-, ethyl ester; 1190897-26-7; UNII-9K7V3V4Y8F; SCHEMBL23346827; ZINC000253909996; AKOS040759626; BDBM50389357
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Hydroxy-8,9-Dihydro-5H-Pyridazino[3,4-D]Azepine-7(6H)-Carboxylate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.