Description

4,5‐Dichloro‐1H,2H,3H‐Pyrrolo[2,3‐B]Pyridin‐2‐One is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused pyrrolopyridine core enables the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, crop protection, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of organic electronic materials and advanced polymers.
• Chemical Synthesis: Versatile scaffold for constructing complex heterocyclic compounds in academic and industrial laboratories.
• Bioconjugation & Probe Development: Useful in creating molecular probes and tagged compounds for biochemical research.

Basic Information

Product Name	4,5‐Dichloro‐1H,2H,3H‐Pyrrolo[2,3‐B]Pyridin‐2‐One
CAS No.	1190315-26-4
Molecular Formula	C7H4Cl2N2O
Molecular Weight	203.03 g/mol
Synonyms	4,5-Dichloro-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-one; 4,5-Dichloro-1,2,3,7-tetrahydro-2-oxopyrrolo[2,3-b]pyridine; 4,5-Dichloro-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 4,5-Dichloro-3H-pyrrolo[2,3-b]pyridin-2(1H)-one; Pyrrolo[2,3-b]pyridin-2-one, 4,5-dichloro-1,2,3,7-tetrahydro-; CAS 1190315-26-4
EINECS	Contact for details

Quality Control

Our production of 4,5‐Dichloro‐1H,2H,3H‐Pyrrolo[2,3‐B]Pyridin‐2‐One adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for verification. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.