Description

Potassium 4-((Morpholino)Methyl)-Phenyltrifluoroborate is a versatile organotrifluoroborate salt, a crucial class of reagents in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, serving as a robust and air-stable alternative to sensitive boronic acids in key cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A stable and efficient aryl source for palladium-catalyzed carbon-carbon bond formation, critical for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly for constructing morpholine-containing scaffolds which are prevalent in medicinal chemistry for their favorable pharmacokinetic properties.
• Agrochemical Product Development: Employed in the synthesis of advanced herbicides, fungicides, and insecticides that require specific aryl-morpholine motifs.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands or functionalized materials used in catalysis and material science.
• Chemical Biology and Probe Development: Useful for the site-specific labeling of biomolecules or the creation of chemical probes for biological target identification.
• Polymer and Material Science: Incorporated into monomers or polymers to introduce specific functional groups, modifying material properties for advanced applications.

Basic Information

Item	Detail
Product Name	Potassium 4-((Morpholino)Methyl)-Phenyltrifluoroborate
CAS No.	1190095-06-7
Molecular Formula	C11H14BF3KNO
Molecular Weight	289.14 g/mol
Synonyms	Potassium (4-(Morpholinomethyl)phenyl)trifluoroborate; 4-(Morpholinomethyl)phenyltrifluoroborate Potassium Salt; [4-(Morpholin-4-ylmethyl)phenyl]trifluoroboranuide Potassium; Potassium Trifluoro(4-((morpholino)methyl)phenyl)borate; 4-Morpholinomethylbenzenetrifluoroborate Potassium Salt; Potassium 4-(Morpholin-4-ylmethyl)phenyltrifluoroborate; (4-(Morpholinomethyl)phenyl)trifluoroborate Potassium; Potassium 4-Morpholinomethylphenyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 4-((Morpholino)Methyl)-Phenyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC for purity assessment, and KF titration for moisture content, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent moisture absorption and decomposition. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹⁹F NMR Purity	≥ 95%
Water Content (KF)	≤ 2.0 %
NMR Solvent Residuals	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.