Description

[Bis(T-Boc)Amino]Methyl Methanethiosulfonate is a specialized, high-purity chemical building block designed for advanced organic synthesis and bioconjugation. This compound is valued for its role as a protected thiol-reactive reagent, enabling controlled and site-specific modifications of biomolecules and polymers under mild conditions. It is essential for researchers and process chemists in pharmaceutical development, proteomics, and materials science who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing protected thiol functionalities.
• Bioconjugation & Protein Labeling: Used for the site-specific modification of peptides, proteins, and antibodies via its methanethiosulfonate group, which reacts selectively with cysteine residues.
• Polymer & Materials Science: Serves as a functional monomer or cross-linking agent for creating advanced polymers with tailored properties, such as stimuli-responsive materials.
• Proteomics Research: Employed in the development of probes and affinity tags for studying protein structure, function, and interactions.
• Linker Chemistry: Facilitates the construction of cleavable linkers used in drug delivery systems, solid-phase synthesis, and combinatorial chemistry.
• Chemical Biology Tool Development: Integral for creating novel chemical tools and assays that investigate biological pathways and mechanisms.

Basic Information

Product Name	[Bis(T-Boc)Amino]Methyl Methanethiosulfonate
CAS No.	1190009-49-4
Molecular Formula	C16H30N2O6S2
Molecular Weight	410.55 g/mol
Synonyms	Bis(tert-butoxycarbonylamino)methyl methanethiosulfonate; (Bis-Boc-amino)methyl methanethiosulfonate; N,N-Bis(tert-butoxycarbonyl)aminomethyl methanethiosulfonate; MTSSL precursor with Boc protection; Boc-protected amino MTS reagent; 1-[(Bis(tert-butoxycarbonyl)amino)methyl] methanesulfonothioate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed under an inert atmosphere if specified and kept in a desiccated environment to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.