Description

2,2′-[(1S,2S)-(+)-1,2-Cyclohexanediylbis[(E)-(Nitrilomethylidyne)]]Bis[4-(tert-Butyl)-6-(4-Morpholinylmethyl)Phenol] is a sophisticated chiral salen-type ligand, a critical component in advanced asymmetric catalysis. This compound matters for its ability to impart high enantioselectivity and catalytic efficiency in complex organic transformations, enabling the synthesis of high-value, optically pure intermediates. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metals (e.g., Mn, Co, Cr) in enantioselective epoxidation, cyclopropanation, and Diels-Alder reactions.
• Pharmaceutical Intermediate Synthesis: For the production of single-enantiomer active pharmaceutical ingredients (APIs) where chirality is crucial for biological activity.
• Agrochemical Research: Development of novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Enabling the synthesis of specialty chemicals, flavors, and fragrances with high optical purity.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis studies.
• Material Science: Potential use in the development of chiral polymers or as a component in advanced sensor systems.

Basic Information

Product Name	2,2′-[(1S,2S)-(+)-1,2-Cyclohexanediylbis[(E)-(Nitrilomethylidyne)]]Bis[4-(tert-Butyl)-6-(4-Morpholinylmethyl)Phenol]
CAS No.	1189364-85-9
Molecular Formula	C38H56N4O4
Molecular Weight	632.88 g/mol
Synonyms	(1S,2S)-N,N'-Bis[3-tert-butyl-5-[(4-morpholinyl)methyl]salicylidene]-1,2-cyclohexanediamine; (1S,2S)-(+)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-tert-butylsalicylidene) derivative; Chiral Salen Ligand (S,S)-Jacobsen-type; (S,S)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine morpholine derivative; Asymmetric Catalyst Ligand; (S,S)-Cyclohexanediamino Salen Ligand; (1S,2S)-H2salen Morpholine Derivative
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to stringent quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized using advanced analytical techniques including HPLC for chiral purity, NMR for structural confirmation, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.