Description

tert-Butoxycarbonylamino-(Tetrahydro-Pyran-4-Yl)-Acetic Acid Methyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical key building block in the development of complex molecules, offering a versatile handle for peptide coupling and further functionalization. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for creating novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Protease Inhibitor Development: Used in the construction of peptidomimetic scaffolds targeting various enzyme families.
• Chemical Biology & Probe Synthesis: Employed to create labeled or modified peptides for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects in fine chemical and CDMO (Contract Development and Manufacturing Organization) settings.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	tert-Butoxycarbonylamino-(Tetrahydro-Pyran-4-Yl)-Acetic Acid Methyl Ester
CAS No.	1188366-14-4
Molecular Formula	C13H23NO5
Molecular Weight	273.33 g/mol
Synonyms	Boc-4-Piperidineacetic Acid Methyl Ester (THP analog); Methyl 2-((tert-butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetate; Boc-Amino(tetrahydro-2H-pyran-4-yl)acetic Acid Methyl Ester; 2-(Boc-amino)-2-(tetrahydropyran-4-yl)acetic acid methyl ester; Boc-Thp-Gly-OMe; N-Boc-4-piperidineglycine methyl ester (tetrahydropyran variant); N-(tert-Butoxycarbonyl)-2-(oxan-4-yl)glycine methyl ester
EINECS	Contact for details

Quality Control

Our tert-Butoxycarbonylamino-(Tetrahydro-Pyran-4-Yl)-Acetic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.