Description

1,4,6-Trichloro-2,3-Dihydro-1H-Indene is a halogenated indane derivative, a versatile chemical intermediate prized for its unique fused-ring structure and reactive chlorine substituents. This compound is critical for synthesizing complex organic molecules, particularly in the development of advanced materials and active pharmaceutical ingredients (APIs). It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Acts as a precursor for developing organic electronic materials, such as charge-transport layers or non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Provides a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution to introduce the indane core into more complex systems.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing specific musky or amber odorants in high-value fragrance chemistry.

Basic Information

Product Name	1,4,6-Trichloro-2,3-Dihydro-1H-Indene
CAS No.	1188146-20-4
Molecular Formula	C9H7Cl3
Molecular Weight	229.51 g/mol
Synonyms	1,4,6-Trichloroindane; 1,4,6-Trichloro-2,3-dihydroindene; 2,3-Dihydro-1,4,6-trichloro-1H-indene; 1H-Indene, 2,3-dihydro-1,4,6-trichloro-; Trichloroindane
EINECS	Contact for details

Quality Control

Every batch of 1,4,6-Trichloro-2,3-Dihydro-1H-Indene is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.